CarboDB Group B antigen 2409

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Group B antigen

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Streptococcus Group B strain M732

Basic Structure

This polysaccharide had a molecular size > 5 x 106. Its main chemical constituents were sialic acid (24%), galactose (25%), a sugar tentatively identified as heptose (21%), glucose (13%), glucosamine (10%) and mannose (7%)

Proposed functions

N/A

Antigenic Nature used to produce antibodies

formalin-killed whole cell vaccines

Carrier Name

nil

Conjugation Method

nil

Antibodies

Antisera

Antibody type and class

N/A

Assay System

Capillary precipitin tests, immunodiffusion tests, immunoelectrophoresis

Cross-reactivity

This antisera cross-reacted with the TCA antigenas well as the EDTA-non pH titrated antigen and the group B antigen extracted with formamide from strain 090R or D136C

Proposed epitopes

L-rhamnose was the immunodominant sugar for the formamide-extracted B antigen

Proposed Utility

This antisera has helped determine that two antigens that react identically with each other and with similar specificities of antibody, yet with different immunodominant determinants

Weblink

PubMed

External Links

• Link to CarboDB database