CarboDB Core oligosaccharide 2299

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Core oligosaccharide

Carbohydrate Class

Core oligosaccharide [LPS]

Source Microbe

Campylobacter fetus

Basic Structure

The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)

Proposed functions

The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab M1357

Antibody type and class

N/A

Assay System

ELISA and immunoblotting

Cross-reactivity

This Mab was highly specific tp C. fetus strains and reacted with serotype A and B strains

Proposed epitopes

N/A

Proposed Utility

Due to its high specificity, this Mab is potentially useful as immunodiagnostic reagent for detection, identification and characterization of C. fetus

Weblink

PubMed

External Links

• Link to CarboDB database