CarboDB Lipopolysaccharide 2231
From DrugPedia: A Wikipedia for Drug discovery
Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Salmonella typhimurium SL 1102 [Re]
Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain
Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
Antigenic Nature used to produce antibodies
Heat killed bacteria
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab MAEC7
Antibody type and class
IgG2b
Assay System
Enzyme immunoassay
Cross-reactivity
This Mab cross-reacted with Rd2 LPS
Proposed epitopes
3-deoxy-D-mannooctulosonic acid [KDO] residues at the terminal non-reducing ends seemed to be the part of the epitope. The particular epitope was proposed to be α-Kdo[2-->4] Kdo
Proposed Utility
This Mab would help elucidate the Kdo LPS domain structure
