CarboDB Core oligosaccharide 2225

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Core oligosaccharide

[edit] Carbohydrate Class

Core oligosaccharide [LPS]

[edit] Source Microbe

Salmonella typhimurium TV 119 [Ra]

[edit] Basic Structure

LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain

[edit] Proposed functions

LPS plays an important virulence role based on its antiphagocytic and endotoxic properties

[edit] Antigenic Nature used to produce antibodies

Heat killed bacteria

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab MAST71

[edit] Antibody type and class

IgG3

[edit] Assay System

enzyme immunoassay, immunoblotting

[edit] Cross-reactivity

This Mab was specific to Ra chemotype

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab would help elucidate the LPS core domain structure

[edit] Weblink

PubMed

[edit] External Links

• IEDB Epitopic Detail

• Link to CarboDB database