CarboDB Lipopolysaccharide 2071

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Pseudomonas aeruginosa strain Fisher IT-3

Basic Structure

The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The core oligosaccharide of P. aeruginosa can be divided into outer and inner core regions. The inner core consists of 2-keto-3-deoxyoctonate (Kdo), heptose, and large amounts of phosphate and is believed to be homogeneous among serotypes. The outer core of P. aeruginosa contains D-glucose (D-Glc), L-rhamnose (L-Rha), D-galactosamine (D-GalN), and L-alanine (L-Ala]

Proposed functions

N/A

Antigenic Nature used to produce antibodies

alkali treated LPS

Carrier Name

nil

Conjugation Method

nil

Antibodies

Antisera

Antibody type and class

N/A

Assay System

ELISA, opsonophagocytic assays, animal protection studies and immunoblotting

Cross-reactivity

This antisera was highly cross-reactive

Proposed epitopes

N/A

Proposed Utility

This antisera had opsonophagocytic activity against LPS rough strains

Weblink

PubMed Central

External Links

• Link to CarboDB database