CarboDB O-polysaccharide 2063
From DrugPedia: A Wikipedia for Drug discovery
Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Carbohydrate Name
O-polysaccharide
Carbohydrate Class
O-polysaccharide [LPS]
Source Microbe
Pseudomonas syringae serogroup O1 strain helianthi CFBP 2149
Basic Structure
O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]
Proposed functions
N/A
Antigenic Nature used to produce antibodies
Whole cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab Ps(1-2)a1
Antibody type and class
IgG1
Assay System
ELISA, agglutination and immunoblotting
Cross-reactivity
"This Mab cross-reacts with chemotypes 1B, 1C-1A, 2A, and 2D-2A but not with those of chemotypes 1C, 1D, 1D-1A, and 2D"
Proposed epitopes
MAb Ps(1-->2)α1 is specific to a region of the linkage between the OPS and the LPS core, which is suggested to be the same in all P. syringae O1 and O2 LPSs
Proposed Utility
This Mab agglutinated heat-killed homologous bacterial cells
