CarboDB O-polysaccharide 2058

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

O-polysaccharide

[edit] Carbohydrate Class

O-polysaccharide [LPS]

[edit] Source Microbe

Pseudomonas syringae IMV K-1025 pv. Atrofaciens

[edit] Basic Structure

O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab Ps1b

[edit] Antibody type and class

IgM

[edit] Assay System

Agglutination, Ouchterlony immunodiffusion, ELISA, SDS-PAGE, and Western immunoblotting

[edit] Cross-reactivity

" P. syringae strains with pathovars glycinea, japonica, striafaciens, atrofaciens and 2 P. syringae strains for which the pathovar(s) has not been identified cross-reacted strongly with the MAb Ps1c"

[edit] Proposed epitopes

The epitope was confined to lateral immunodominant substituents of (α1-->3)D-Rha, (β1-->4)D-GlcNAc, and (α1-->4)D-Fuc, respectively, which are all bound to the backbone-located D-rhamnose

[edit] Proposed Utility

This Mab strongly agglutinated homologous bacterial cells and precipitated soluble antigens

[edit] Weblink

PubMed Central

[edit] External Links

• Link to CarboDB database