CarboDB Capsular polysaccharide 1858

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Contents

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Neisseria meningitidis group C strain C11

Basic Structure

It consists of a homopolymer of α(2-->9)-linked sialic acid residues


Proposed functions

It is an important virulence factor

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 3079.6

Antibody type and class

IgG3

Assay System

Fluorescence ELISA, Ouchterlony precipitation, Bacterial agglutination assay, Bactericidal assay

Cross-reactivity

This Mab reacted with natural O-acetyl-negative variant (OAc-, strain MC19) polysaccharide and did not react with K1 polysaccharide

Proposed epitopes

N/A

Proposed Utility

This Mab had bactericidal activity

Weblink

PubMed

External Links