CarboDB Capsular polysaccharide 1805

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Neisseria meningitidis Serogroup W135

[edit] Basic Structure

It consists of a homopolymer of α(2-->8)-linked sialic acid residues

[edit] Proposed functions

It is an important virulence factor

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 6G9-7

[edit] Antibody type and class

IgG3

[edit] Assay System

ELISA

[edit] Cross-reactivity

This Mab was specific to Serogroup W1354 and did not cross-react with other serogroups even though weak reactions was seen with cells of serogroup D and L meningococci

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab would help in serogrouping of Neisseria meningitidis strains

[edit] Weblink

PubMed Central

[edit] External Links

• BCSDB Structural Detail

• Link to CarboDB database