CarboDB Lipopolysaccharide 1533

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Klebsiella pneumoniae strain R20/O1

Basic Structure

N/A

Proposed functions

It is an important virulence factor

Antigenic Nature used to produce antibodies

heat-killed Klebsiella pneumoniae strain R20/O1

Carrier Name

nil

Conjugation Method

nil

Antibodies

Un-named Mab

Antibody type and class

N/A

Assay System

ELISA and immunoblotting

Cross-reactivity

The antibody was able to bind to LPS of clinical isolates of K. pneumoniae, K. oxytoca, K. terrigena and K. planticola but did not bind to LPS of other Gram-negative genera

Proposed epitopes

This Mab recognized the LPS core

Proposed Utility

This antibody bound only to those LPS molecules which did not carry an O-antigen and thus this antibody is different from those already published

Weblink

PubMed

External Links

• Link to CarboDB database