CarboDB Lipopolysaccharide 1514

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Klebsiella strains KD37

[edit] Basic Structure

O-1 side chain of the LPS is proposed to contain a disaccharide repeat unit consisting of [-α-D-Galp-(1->3)-β-D-Galf-] (1->4), where Gal is galactose

[edit] Proposed functions

These major cell surface antigens play important roles in the ability of the bacterium to evade host cell defenses

[edit] Antigenic Nature used to produce antibodies

formalinized whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Polysera

[edit] Antibody type and class

N/A

[edit] Assay System

ELISA and immunoblotting

[edit] Cross-reactivity

This antisera reacted with the full complement of High molecular weight LPS and Low molecular weight LPS but had no apparent response against the lipid A core

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This antibody may help in the stuctural and functional elucidation of O1 side chain of Klebsiella LPS

[edit] Weblink

PubMed Central

[edit] External Links

• Link to CarboDB database