CarboDB Capsular polysaccharide 1509

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Actinobacillus pleuropneumoniae serotype b strain 81-750

[edit] Basic Structure

Consists of a common backbone consisting of disaccharide repeating units, [->6)-α-DGlcpNAc (1-->5)-β-Kdop-(2-->]n, but, in addition, the CPS of serotype 5b has a lateral β-D-glucopyranosyl residue

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

formaldehyde killed cells and 2 injections with tetanus toxoid CPS strain L20 conjugate (CPS L20-TT)

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 2C3

[edit] Antibody type and class

IgG2b

[edit] Assay System

ELISA and dot ELISA

[edit] Cross-reactivity

This antibody cross-reacted strongly with LPS and CPS of serotype 5a

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals

[edit] Weblink

PubMed Central

[edit] External Links

• Link to CarboDB database