CarboDB Capsular polysaccharide 1465

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Enterococcus faecalis 12030

[edit] Basic Structure

Glycerol teichoic acid-like molecules with a carbohydrate backbone structure of 6-α-D-glucose- 1-->2 glycerol-3-PO4 with substitution on carbon 2 of the glucose with an α-2-1-D-glucose residue

[edit] Proposed functions

These polysaccharides are major virulence factors

[edit] Antigenic Nature used to produce antibodies

Capsular polysaccharide

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Polysera

[edit] Antibody type and class

IgM

[edit] Assay System

ELISA and opsonophagocytic assay

[edit] Cross-reactivity

The antisera cross-reacted with Enterococcus faecalis OG1RF and against two serologically related, vancomycin-resistant Enterococcus faecium clinical isolates

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

These antibodies may be useful for prophylaxis and treatment of enterococcal infections

[edit] Weblink

PubMed

[edit] External Links

• BCSDB Structural Detail

• Link to CarboDB database