CarboDB Exopolysaccharide 1252

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Exopolysaccharide

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Burkholderia pseudomallei NCTC 4845

[edit] Basic Structure

N/A

[edit] Proposed functions

Polysaccharide capsule of B. pseudomallei plays a role in environmental protection, immune system evasion and attachment to epithelial cells

[edit] Antigenic Nature used to produce antibodies

Heat inactivated B. pseudomallei NCTC 4846

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 3VIE5

[edit] Antibody type and class

IgG2b

[edit] Assay System

ELISA and immunoblotting

[edit] Cross-reactivity

N/A

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This MAb demonstrated a significant protective effect against a challenge dose of B. Pseudomallei in mice

[edit] Weblink

PubMed

[edit] External Links

• Link to CarboDB database