CarboDB Glucan 1042

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Glucan

Carbohydrate Class

Miscellaneous

Source Microbe

Neurospora crassa

Basic Structure

Glucans are a heterogeneous group of glucose polymers, consisting of a backbone of β(1-->3)-linked β-D-glucopyranosyl units with β(1-->6)-linked side chains of varying distribution and length

Proposed functions

Activates leukocytes, stimulating their phagocytic, cytotoxic, and antimicrobial activities, including the production of reactive oxygen and nitrogen intermediates

Antigenic Nature used to produce antibodies

Homogenous suspension of hyphal walls.

Carrier Name

nil

Conjugation Method

nil

Antibodies

S4D1

Antibody type and class

IgM

Assay System

ELISA, immunofluorescence

Cross-reactivity

This antibody was cross-reactive with A.nidulans, Schiz.commune.

Proposed epitopes

1,3-α-glucan

Proposed Utility

Screening of fungi for presence of 1,3-α-glucan in hyphae cell wall.

Weblink

PubMed

External Links

• Link to CarboDB database