Rv2747
From DrugPedia: A Wikipedia for Drug discovery
| Rv2747
| |
| Name | |
| N-acetylglutamate synthase | |
| Identifiers | |
| Swiss Prot | |
| Genbank | |
| PDB | |
| Chemical data | |
| Formula | C18H20ClNO3 [1] |
| Mol. wt. | 19557 Da |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Solubility | ? |
| Isoelectric-Point | 5.27 |
Contents |
General
INVOLVED IN ARGININE BIOSYNTHESIS [CATALYTIC ACTIVITY: L-GLUTAMATE + ACETYL-COA <=> N-ACETYL-L-GLUTAMATE + COENZYME A]
Essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) mutants available at TARGET website
Protein Sequence
>Rv2747, TB.seq 3059259:3059780 MW:19557 VTERPRDCRPVVRRARTSDVPAIKQLVDTYAGKILLEKNLVTLYEAVQEFWVAEHPDLYGKVVGCGALHVLWSDLGEIRT VAVDPAMTGHGIGHAIVDRLLQVARDLQLQRVFVLTFETEFFARHGFTEIEGTPVTAEVFDEMCRSYDIGVAEFLDLSYV KPNILGNSRMLLVL
Human Homologue Blast Result
| subject ids | % identity | % positives | alignment length | evalue |
| sp|Q9UHF3.1 | 31 | 40 | 118 | 0.027 |
| sp|Q9H967.1 | 29 | 42 | 87 | 0.73 |
| sp|Q8IY67.1 | 27 | 40 | 93 | 2.5 |
| sp|Q9Y2K9.2 | 27 | 47 | 61 | 3.8 |
| sp|Q92621.2 | 31 | 45 | 72 | 7.5 |
Alergen Protein
Link to Algpred
Non Allergen Predicted by AlgPred Server
Bacterial Toxin Prediction
Link to btxpred
No Hit Fountd by btxpred server.
Subcellular Location
Link to TBpred
Cytoplasmic
Antigens
No Hit Found in AntigenDB
No. Hit Found in IEDB
B cell Epitopes
BCEpred Analysis
Link to Bcepred
Result Predicited by [2]
ABCpred Analysis
Link to ABCpred
Result Predicited by [3]
IEDB Analysis
Link to IEDB
Result Predicited by [4]
MHC Class-I Binder
nHLAPred Analysis
Link to nHLApred
Result Predicited by [5]
IEDB Analysis
Link to IEDB
Result Predicted by [6]
MHC Class-II Binder
Propred Analysis
Link to Propred
Result Predicted by [7]
NetMHC-II Analysis
Link to NetMHC-II
Result Predicted by [8]
External Links
- Database of Mycobacterium tuberculosis genome sequences and related information.
