From DrugPedia: A Wikipedia for Drug discovery

Immunoatation of Rv2992c
Name
Glutamyl-tRNA synthetase
Identifiers
Swiss Prot	P0A636
Genbank	887850
PDB	2JA2
Chemical data
Formula	C16H13F3N2O3 [1]
Mol. wt.	53831.9 Da
Pharmacokinetic data
Bioavailability	?
Solubility	?
Isoelectric-Point	5.58

Contents 1 General 1.1 Protein Sequence 2 Human Homologue Blast Result 3 Alergen Protein 4 Bacterial Toxin Prediction 5 Subcellular Location 6 Antigens 6.1 B cell Epitopes 6.1.1 BCEpred Analysis 6.1.2 ABCpred Analysis 6.1.3 IEDB Analysis 7 MHC Class-I Binder 7.1 nHLAPred Analysis 7.2 IEDB Analysis 8 MHC Class-II Binder 8.1 Propred Analysis 8.2 NetMHC-II Analysis 9 External Links

General

INVOLVED IN TRANSLATION MECHANISMS [CATALYTIC ACTIVITY: ATP + L-GLUTAMATE + TRNA(GLU) = AMP + DIPHOSPHATE + L-GLUTAMYL-TRNA(GLU)].

Protein Sequence

>Rv2992c, TB.seq 3348805:3350274 MW:53833 VTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGG PYGPYRQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDAQRAAYLAEGRQPVVRLRM PDDDLAWNDLVRGPVTFAAGSVPDFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAER IPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFD QKKADALNAEHIRMLDVGDFTVRLRDHLDTHGHHIALDEAAFAAAAELVQTRIVVLGDAWELLKFFNDDQYVIDPKAAAK ELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRL RAARQLVGHA

Human Homologue Blast Result

subject ids	% identity	% positives	alignment length	evalue
sp|Q5JPH6.2|	38	52	331	6e-52
sp|P47897.1|	24	39	308	6e-11
sp|P07814.4	23	40	220	5e-04
sp|Q5THR3.1	27	38	201	0.11
sp|Q2TB90.2	41	46	43	3.9

Alergen Protein

Link to Algpred
Non Allergen Predicted by AlgPred Server

Bacterial Toxin Prediction

Link to btxpred
No Hit Fountd by btxpred server.

Subcellular Location

Link to TBpred
Cytoplasm

Antigens

No Hit Found in AntigenDB
No. Hit Found in IEDB

B cell Epitopes

BCEpred Analysis

Link to Bcepred
Result Predicited by

ABCpred Analysis

Link to ABCpred
Result Predicited by

IEDB Analysis

Link to IEDB
Result Predicited by

MHC Class-I Binder

nHLAPred Analysis

Link to nHLApred
Result Predicited by

IEDB Analysis

Link to IEDB
Result Predicted by

MHC Class-II Binder

Propred Analysis

Link to Propred
Result Predicted by

NetMHC-II Analysis

Link to NetMHC-II
Result Predicted by

External Links

• Database of Mycobacterium tuberculosis genome sequences and related information.