Immunotation of Rv3340
From DrugPedia: A Wikipedia for Drug discovery
Immunotation of Rv3340
| |
Name | |
O-acetylhomoserineaminocarboxypropyltransferase | |
Identifiers | |
Swiss Prot | |
Genbank | |
PDB | ? |
Chemical data | |
Formula | [] |
Mol. wt. | 47370.6 Da |
Pharmacokinetic data | |
Bioavailability | ? |
Solubility | ? |
Isoelectric-Point | 5.19 |
Contents |
General
In enzymology, an O-acetylhomoserine aminocarboxypropyltransferase is an enzyme that catalyzes the chemical reaction
O-acetyl-L-homoserine + methanethiol --- L-methionine + acetate
Thus, the two substrates of this enzyme are O-acetyl-L-homoserine and methanethiol, whereas its two products are L-methionine and acetate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase. Other names in common use include O-acetyl-L-homoserine acetate-lyase (adding methanethiol), O-acetyl-L-homoserine sulfhydrolase, O-acetylhomoserine (thiol)-lyase, O-acetylhomoserine sulfhydrolase, and methionine synthase. This enzyme participates in methionine metabolism and cysteine metabolism.
Protein Sequence
>Rv3340, TB.seq 3726123:3727469 MW:47372 MSADSNSTDADPTAHWSFETKQIHAGQHPDPTTNARALPIYATTSYTFDDTAHAAALFGLEIPGNIYTRIGNPTTDVVEQ RIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLGIEVSFVDDPDDLDTWQAAVRPNT KAFFAETISNPQIDLLDTPAVSEVAHRNGVPLIVDNTIATPYLIQPLAQGADIVVHSATKYLGGHGAAIAGVIVDGGNFD WTQGRFPGFTTPDPSYHGVVFAELGPPAFALKARVQLLRDYGSAASPFNAFLVAQGLETLSLRIERHVANAQRVAEFLAA RDDVLSVNYAGLPSSPWHERAKRLAPKGTGAVLSFELAGGIEAGKAFVNALKLHSHVANIGDVRSLVIHPASTTHAQLSP AEQLATGVSPGLVRLAVGIEGIDDILADLELGFAAARRFSADPQSVAAF
.3|CGL_HUMAN RecName: Full=Cystathionine gamma-lyase... 211 Gene info .3|CDC23_HUMAN RecName: Full=Cell division cycle pro... 31.2 Gene info .1|MYOME_HUMAN RecName: Full=Myomegalin; AltName: Fu... 30.0 Gene info .2|DYH9_HUMAN RecName: Full=Dynein heavy chain 9, ax... 29.6
Human Homologue Blast Result
subject ids | % identity | % positives | alignment length | evalue |
sp|P32929 | 34 | 52 | 403 | 8e-55 |
sp|Q9UJX2 | 23 | 42 | 94 | 1.2 |
sp|Q5VU43 | 35 | 50 | 62 | 2.8 |
sp|Q9NYC9 | 30 | 47 | 71 | 4.2 |