Combinatorial Chemistry

From DrugPedia: A Wikipedia for Drug discovery

Combinatorial Chemistry is a process of synthesizing many different substances quickly and at the same time.In traditional chemistry the chemist synthesize a particular compound and if synthesis of it involve the large number of steps then at each steps the intermediates is purified.On the other hand, when chemists use combinatorial methods they will always be making many different compounds at the same time often in the same reaction vessel.So this process reduces the time and labor involved in traditional chemistry methods where compounds are synthesized individually, one at a time.Combinatorial chemists can create thousands of compounds in just days. They need rapid and inexpensive ways of screening such large numbers of compounds. Consequently they developed robotics and automated methods to help them with these screenings. This need to be able to rapidly screen huge numbers of compounds has spawned its own discipline known as High Throughput Screening.