5-hydroxytryptamine 1A-alpha receptor

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Contents

[edit] Source Organism

Fugu rubripes (Japanese pufferfish) (Takifugu rubripes).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu.

[edit] Subcellular Localization

Cell membrane; multi-pass membrane protein.

[edit] Developmental Stage

[edit] Similarity

Belongs to the G-protein coupled receptor 1 family.

[edit] Post translational Modification

[edit] Function

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity).