Hormone receptor 4
From DrugPedia: A Wikipedia for Drug discovery
Contents |
[edit] Source Organism
Drosophila melanogaster (Fruit fly).
[edit] Taxomomy
Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
[edit] Subcellular Localization
Nucleus.
[edit] Developmental Stage
[edit] Similarity
Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
[edit] Post translational Modification
[edit] Function
Coordinates growth and maturation by mediating endocrine responses to the attainment of critical weight during larval development. Plays a central role in the genetic cascades triggered by the steroid hormone ecdysone at the onset of metamorphosis, acting as both a repressor of the early ecdysone- induced regulatory genes and an inducer of the ftz-f1 midprepupal competence factor.
