Prostaglandin F2alpha
From DrugPedia: A Wikipedia for Drug discovery
|
|
| Prostaglandin F2alpha
| |
| Systematic (IUPAC) name | |
| (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C20H34O5 |
| Mol. mass | 354.48 |
| SMILES | & |
| Physical data | |
| Melt. point | 30(EXP) °C |
| Solubility in water | 2.58(EST) mg/mL |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.Dinoprost (INN, prostaglandin F2α or PGF2α in prostanoid nomenclature) is a naturally-occurring prostaglandin used in medicine to induce labor and as an abortifacient.
[edit] General Properties
*Molecular Weight
354.48
*Molecular Formula
C20H34O5
*IUPAC NAME
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid
*Canonical Smiles
CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O
*Isomeric Smiles
CCCCC[C@@H](C=C[C@H]1[C@@H](C[C@@H]([C@@H]1CC=C/CCCC(=O)O)O)O)O
[edit] PhysioChemical Properties
*Melting Point
30(EXP)
*LogP
4.39(EXP)
*Water Solubility
2.58(EST)
