Desoxycorticosterone acetate

Revision as of 08:45, 19 February 2009 by Arun sharma (Talk | contribs)

Description

21-Hydroxypregn-4-ene-3,20-dione. Desoxycorticosterone acetate (DOCA) is used as replacement therapy in ADDISON DISEASE.

*Molecular Weight

372.5

*Molecular Formula

C₂₃H₃₂O₄

*IUPAC NAME

[2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

*Canonical Smiles

CC(=O)OCC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C

*Isomeric Smiles

CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

*Melting Point

157(EXP)

*LogP

3.08(EXP)

*Water Solubility

8.73(EXP) at 25C