Betamethasone 17-Valerate

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

Show 3-D Structure

The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.

General Properties

*Molecular Weight

476.58

*Molecular Formula

C₂₇H₃₇FO₆

*IUPAC NAME

[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate

*Canonical Smiles

CCCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO

*Isomeric Smiles

CCCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO

PhysioChemical Properties

*Melting Point

183-184(EXP)

*LogP

3.6(EXP)

*Water Solubility

9.29(EXP) at 25C

External Links

• [1]Pubchem
• [2]]KEGG Drug
• [3]Drugbank

Categories:Hormones