Dehydroepiandrosterone
From DrugPedia: A Wikipedia for Drug discovery
Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
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Description
A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
General Properties
*Molecular Weight
288.42
*Molecular Formula
C19H28O2
*IUPAC NAME
(3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
*Canonical Smiles
CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C
*Isomeric Smiles
C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)O)C
PhysioChemical Properties
*Melting Point
140-141(EXP)
*LogP
3.23(EXP)
*Water Solubility
63.5(EXP) at 25C
