Haemophilus ducreyi
From DrugPedia: A Wikipedia for Drug discovery
Haemophilus ducreyi
It is a fastidious gram-negative coccobacillus causing the sexually transmitted disease chancroid, a major cause of genital ulceration in developing countries characterized by painful sores on the genitalia.
| Kingdom | Bacteria |
|---|---|
| Phylum | Proteobacteria |
| Class | Gamma Proteobacteria |
| Order | Pasteurellales |
| Family | Pasteurellaceae |
| Genus | Haemophilus |
| Species | H. ducreyi |
| Binomial | Haemophilus ducreyi |
Contents |
Surface Characteristics
It consist of an oligosaccharide core ketosidically linked via a 3-deoxy-D-manno-octulosonic acid (Kdo) residue to the lipid A region. The oligosaccharide core characteristic of these bacteria has been divided into two regions: (i) an inner core, consisting of three L-glycero-D-manno-heptose (Hep) residues and one phosphorylated Kdo residue, and (ii) an outer core, with one or more heterogeneous oligosaccharide branches containing mainly galactose (Gal) and glucose (Glc) residues.
Transmission
Haemophilus ducreyi is an opportunistic microorganism that infects its host by way of breaks in the skin or epidermis.
Pathogenic Activity
Haemophilus ducreyi is an opportunistic microorganism that infects its host by way of breaks in the skin or epidermis. Inflammation then takes place as the area of infection is inundated with lymphocytes, macrophages and granulocytes.
