PolysacDB Cell wall polysaccharide 2425

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Cell wall polysaccharide

Carbohydrate Class

Miscellaneous

Source Microbe

Streptococcus mutans LM7 Serotype e

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab S3-9

Antibody type and class

IgM

Assay System

Radioimmunoassay, Immunodiffusion tests

Cross-reactivity

Mab S3-9 reacted with hot-saline extracts of strain LM7, MT703, and P4 (type e) cells but did not react at all with extracts of other S. mutans strains

Proposed epitopes

β-glucosyl moiety of the e-polysaccharide seemed to make up the immunodominant region

Proposed Utility

This Mab can be used for immunodetection of serotype e Streptococcal cells

Weblink

PubMed Central

External Links

• Link to PolysacDB database