PolysacDB Lipopolysaccharide 2182
From DrugPedia: A Wikipedia for Drug discovery
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Serogroup C1 (0:6,7) Salmonella
Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-β-D-Manp-(1-->2)-α-D-Manp [branched to α-D-Glcp-(1-->3)] -(1-->2)-α-D-Manp-(1-->2)-α-D-Manp-(1-->3)-β-D-GlcpNAc-(1-
Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
Antigenic Nature used to produce antibodies
Whole cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab Cl-1
Antibody type and class
IgG3
Assay System
ELISA, slide agglutination test
Cross-reactivity
This Mab reacted strongly with all strains of serogroup C1 Salmonella that have either O:6(1),7, O:6(2),7, or O:6(1,2),7 antigens and also reacted with the phage-14 lysogenized C1 strains that bear the phage-modified O antigen (O:6,7----O:6,7,14)
Proposed epitopes
N/A
Proposed Utility
This Mab can be used for the diagnosis of serogroup C1 salmonella
