PolysacDB Vi antigen 2175

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Vi antigen

Carbohydrate Class

Miscellaneous

Source Microbe

Salmonella typhi 620Ty

Basic Structure

Vi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Purified Vi antigen

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab Vi4a

Antibody type and class

IgG2b

Assay System

passive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay

Cross-reactivity

This Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains

Proposed epitopes

N/A

Proposed Utility

The Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi

Weblink

PubMed Central

External Links

• Link to PolysacDB database