PolysacDB O-polysaccharide 2061

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

O-polysaccharide

Carbohydrate Class

O-polysaccharide [LPS]

Source Microbe

Pseudomonas syringae GSPB 883 pv. Morsprunorum

Basic Structure

O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab Ps2a

Antibody type and class

IgG1

Assay System

Agglutination, Ouchterlony immunodiffusion, ELISA, SDS-PAGE, and Western immunoblotting

Cross-reactivity

MAb Ps2a reacted with 20 of the 21 strains with pathovar morsprunorum

Proposed epitopes

The epitope was confined to D-Rha(α1-->3)D-Rha sequences of the linear O-polysaccharide

Proposed Utility

This Mab was useful for elucidation of the LPs structure

Weblink

PubMed Central

External Links

• Link to PolysacDB database