PolysacDB Lipopolysaccharide 1906

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Pasteurella multocida serotype 12

Basic Structure

LPS molecule is composed of three regions consisting of lipid A, core oligosaccharides, and O-antigen polysaccharides

Proposed functions

LPS is well known for its biological activities, including modification of metabolic activity and phagocytic function, alteration of migration of neutrophils and macrophages, and mitogenesis of lymphocytes

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Antisera

Antibody type and class

N/A

Assay System

ELISA

Cross-reactivity

This antisera cross-reacted with serotype 4 cells

Proposed epitopes

N/A

Proposed Utility

This antisera may be useful in defining antigenic determinants of LPS.

Weblink

PubMed Central

External Links

• Link to PolysacDB database