PolysacDB Capsular polysaccharide 1803

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Neisseria meningitidis Serogroup C

Basic Structure

It consists of a homopolymer of α(2-->8)-linked sialic acid residues

Proposed functions

It is an important virulence factor

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 4-2-C

Antibody type and class

IgG3

Assay System

ELISA

Cross-reactivity

This Mab was specific to Serogroup C and did not cross-react with other serogroups

Proposed epitopes

N/A

Proposed Utility

This Mab would help in serogrouping of Neisseria meningitidis strains

Weblink

PubMed Central

External Links

• BCSDB Structural Detail

• Link to PolysacDB database