PolysacDB Lipoarabinomannan 1649

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipoarabinomannan

Carbohydrate Class

Miscellaneous

Source Microbe

Mycobacterium leprae

Basic Structure

Lipoarabinomannan is a complex carbohydrate containing arabinose, mannose, glycerol, and myo-inositol 1-phosphate, in addition to lactate, succinate, palmitate, and 10 methyloctadecanoate

Proposed functions

T cell proliferation and to interfere with gamma interferon-mediated activation of macrophages

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 908

Antibody type and class

IgG3

Assay System

ELISA

Cross-reactivity

This Mab cross-reacted with M. tuberculosis

Proposed epitopes

N/A

Proposed Utility

This Mab would help in the structure elucidation of lipoarabinomanna

Weblink

PubMed Central

External Links

• BCSDB Structural Detail

• Link to PolysacDB database