PolysacDB Lipopolysaccharide 1505

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Actinobacillus pleuropneumoniae serotype b strain 81-750

Basic Structure

Consists of linear unbranched polysaccharide structure

Proposed functions

LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus

Antigenic Nature used to produce antibodies

formaldehyde killed cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 1B2

Antibody type and class

IgM

Assay System

ELISA and dot ELISA

Cross-reactivity

This antibody cross-reacted strongly with strain CPS of serotype 5b

Proposed epitopes

N/A

Proposed Utility

This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals

Weblink

PubMed Central

External Links

• Link to PolysacDB database