PolysacDB GP15 glycoprotein 1382

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

GP15 glycoprotein

Carbohydrate Class

Miscellaneous

Source Microbe

Cryptosporidium parvum

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

oocysts of C. Parvum

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 5C3

Antibody type and class

IgA

Assay System

ELISA, immunoblotting and immunoelectron microscopy

Cross-reactivity

This Mab did not cross-react with Cryptosporidium. Baileyi, Cryptosporidium muris, Cryptosporidium serpentis, Besnoitia darlingi,Caryospora bigenetica, Eimeria nieschulzi, E. papillata and Toxoplasma gondii

Proposed epitopes

N-acetylglucosamine residues seemed to be an important part of the epitope

Proposed Utility

This Mab showed invivo protection against Chlamydia infection

Weblink

PubMed Central

External Links

• Link to PolysacDB database