PolysacDB Mannan 1346

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Mannan

Carbohydrate Class

Miscellaneous

Source Microbe

Candida albicans NIH B-792

Basic Structure

An α-linked branched homopolymer of mannose linked to protein

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Polyclonal Antisera

Antibody type and class

N/A

Assay System

Ouchterlony double immunodiffusion

Cross-reactivity

The antisera cross-reacted with C. albicans NIH A-207 and Hormodendrum strains, H. pedrosoi IFO 6071, H. compactum IFO 6726, and H. dermatitidis IFO 6421

Proposed epitopes

The epitope was proposed to consist of α-D-mannopyranosyl residues occupying the nonreducing terminals of the branching moieties

Proposed Utility

This antisera was used to study the structural similarities between Candida mannans and Hormemendrum galactomannans

Weblink

External Links

• BCSDB Structural Detail

• IEDB Epitopic Detail

• Link to PolysacDB database