PolysacDB Lipopolysaccharide 1250

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Brucella abortus 2308

Basic Structure

Brucella LPS-PS complexes consist of the Brucella O-chains, native hapten, and polysaccharide B

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole Brucella. Abortus 2308 cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab A

Antibody type and class

N/A

Assay System

Immunoblotting, ELISA, immunoaffinity chromatography, immunoprecipitation,

Cross-reactivity

This antibody was specific to Brucella abortus 2308 strain and did not cross-react with Brucella melitiensis 16M strain and Brucella abortus type 4 strains. It reacted with Brucella abortus 19 strain

Proposed epitopes

This mab was specific to the A epitope

Proposed Utility

This Mab would provide a tool to monitor the expression of LPS epitopes by Brucella spp. and determine the content of preparations intended for use in the control of brucellosis

Weblink

PubMed Central

External Links

• Link to PolysacDB database