PolysacDB Lipopolysaccharide 1195
From DrugPedia: A Wikipedia for Drug discovery
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Brucella abortus 1119-3
Basic Structure
N/A
Proposed functions
N/A
Antigenic Nature used to produce antibodies
Killed whole cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
B.ab.-4
Antibody type and class
IgG3
Assay System
Whole cell agglutination, immunodiffusion, immunoblotting and ELISA
Cross-reactivity
This Mab cross-reacted with LPS and 0-chains of Y. enterocolitica and B. abortus and exhibited high ELISA titers with homologous and heterologous antigens, in addition to agglutinating activity for both bacteria
Proposed epitopes
this Mab was proposed to be directed to antigenic determinants present along the length of the polymeric O-chain
Proposed Utility
This Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.
