PolysacDB Lipopolysaccharide 1170

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Bordetella bronchiseptica

Basic Structure

The O-chain of these bacteria was reported as a homopolymer of 1,4-linked 2,3-diacetamido-2,3- dideoxy-α-galacturonic acid. This polymer contains several amidated uronic acids, the number of which varies between strains

Proposed functions

N/A

Antigenic Nature used to produce antibodies

LPS from B. bronchiseptica

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab BRg1

Antibody type and class

IgM

Assay System

ELISA and ELISA Inhibition assay

Cross-reactivity

This Mab did not react with the B. pertussis LPS

Proposed epitopes

BRgl interacts with a structure located at the hinge between the polymeric O-chains and a core region

Proposed Utility

This Mab was used for structurural elucidation of the epitope

Weblink

PubMed

External Links

• BCSDB Structural Detail

• Link to PolysacDB database