PolysacDB Lipopolysaccharide 1089

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Eikenella corrodens FDC 1073

Basic Structure

The LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities

Proposed functions

The lipopolysaccharide (LPS) of the species may play a primary role in the pathogenesis

Antigenic Nature used to produce antibodies

LPS preparations from E. corrodens FDC

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab ECF-3

Antibody type and class

IgG3

Assay System

ELISA, immunodiffusion, immunoblotting

Cross-reactivity

This antibody cross-reacted with LPSs from C. ochracea M-12 and F. necrophorum ATCC 25286

Proposed epitopes

The epitope consists of D-galactose and L-rhamnose residues and recognizes an O-side chain epitope

Proposed Utility

This Mab would help in the revealing of antigenic natureof the surface of Eikenella corrodens

Weblink

[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC313151 &tool=pmcentrez&rendertype=abstract PubMed Central]

External Links

• Link to PolysacDB database