PolysacDB Lipopolysaccharide 1050

From DrugPedia: A Wikipedia for Drug discovery

Revision as of 06:02, 8 April 2010 by Raghavagps (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search


Contents

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Escherichia coli strain J5 (chemotype Rc)

Basic Structure

The core oligosaccharide part of the LPS consists of the following residues : α-D-Glcp(1-->2)α-D-Glcp(1-->2)α-D-Glcp [branched to α-D-GlcpNAc(1-->3)] (1-->3)α-L-D-man-Hepp [branched to α-D-GlcpNAc(1-->7)α-L-D-man-Hepp(1-->7)] and [branched to a phosphate group] (1-->3)α-L-D-man-Hepp [branched to α-Kdop(2-->4)α-Kdop(2-->4)α-Kdop(2-6)Subst] and [branched to a phosphate group](1-->5)


Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 4

Antibody type and class

IgG2a

Assay System

ELISA, Limulus assay, invivo protection assay

Cross-reactivity

This antibody ross-reacted with Salmonella minnesota strain R5

Proposed epitopes

Terminal glucose residues

Proposed Utility

N/A

Weblink

[http://www.ncbi.nlm.nih.gov/pubmed/2455054 ?dopt=Abstract' PubMed]

External Links