PolysacDB Lipopolysaccharide 1038
From DrugPedia: A Wikipedia for Drug discovery
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Rhizobium leguminosarum
Basic Structure
LPS is composed of three parts: (1) lipid A, (2) core polysaccharide, and (3) O antigen. The lipid A region contains two glucosamine sugar derivatives, each with three fatty acids and phosphate or pyrophosphate attached. The core polysaccharide has KDO and attached to lipid A. The side chain O is small polysaccharide chain extending outward from the core, it has several peculiar sugars and varies in composition between bacterial strains.
Proposed functions
LPS is most unusual constituents of outer membrane. It plays important role in host defence avoidance. LPS contributes to the negative charge of the bacterial surface. Lipid A is often toxic and act as endotoxin
Antigenic Nature used to produce antibodies
Mixture of suspension of cell envelop.
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab 3
Antibody type and class
N\A
Assay System
Western blotting, spot imunoassays, agglutination tests
Cross-reactivity
This antibody was cross-reactive with different strains of R.leguminosarum like R.biovars viciae, trifolli and phaseoli.
Proposed epitopes
N/A
Proposed Utility
N\A
