CarboDB Capsular polysaccharide 1522

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Klebsiella pneumoniae

Basic Structure

N/A

Proposed functions

CPS have been shown to be important virulence factors and potent Ag for the induction of immunoprotection

Antigenic Nature used to produce antibodies

A 24-valent K. pneumoniae CPS vaccine containing the serotypes 2, 3, 5, 9, 10, 15, 16. 17, 18, 21, 22, 25, 28. 30, 35, 43, 52, 53, 55, 60, 61, 62, 63, and 64

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab MT72 H99

Antibody type and class

IgM

Assay System

ELISA and immunofluorescence

Cross-reactivity

This Mab recognised K5, K6, K7, K10, K20, K49, K61, K62, K64 and K74 strains

Proposed epitopes

N/A

Proposed Utility

This Mab may prove valuable as diagnostic tools and that an immunotherapy is feasible

Weblink

PubMed

External Links

• Link to CarboDB database