CarboDB High molecular weight polysaccharide 1143
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Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Carbohydrate Name
High molecular weight polysaccharide
Carbohydrate Class
Miscellaneous
Source Microbe
Bacteroides fragilis NCTC 9343
Basic Structure
-3)α-D-FucpNAc4N(1-->4)α-D-GalpNAc [branched to β-D-Galf(1-->3)] (1-->3)β-D-Galp [branched via 6th and 4th positions to RPyr(2-(1-.C73
Proposed functions
Capsular polysaccharide of B. fragilis may represent a virulence factor
Antigenic Nature used to produce antibodies
whole cells of a B. fragilis NCTC 9343 enriched for expression of the EDL
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab QUBf5
Antibody type and class
IgG2b
Assay System
Immunoblotting, immunofluorescence, flow cytometry
Cross-reactivity
This Mab did not cross-react with B. vulgatus, B. thetawtaomicron, B. ovatus, B. distasonis, B. gingivalis, E. coli or S. aureus. But it reacted with B. fragilis strain BE3
Proposed epitopes
N/A
Proposed Utility
N/A
