Alpha-2Db adrenergic receptor
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Source Organism
Danio rerio (Zebrafish) (Brachydanio rerio).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio.
Subcellular Localization
Cell membrane; multi-pass membrane protein.
Developmental Stage
Similarity
Belongs to the G-protein coupled receptor 1 family.
Post translational Modification
Function
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine = epinephrine > oxymetazoline.
