Insulin receptor7101)
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Source Organism
Macaca mulatta (Rhesus macaque).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Developmental Stage
Similarity
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain.
Post translational Modification
Autophosphorylated on tyrosine residues in response to insulin (By similarity).
Function
This receptor binds insulin and has a tyrosine-protein kinase activity.
