Orphan nuclear receptor NR4A1
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Source Organism
Mus musculus (Mouse).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular Localization
Nucleus.
Developmental Stage
Highest levels are found in the adult with barely detectable levels in pre- and early postnatal tissue.
Similarity
Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post translational Modification
Function
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration.
