Diuretic hormone class 1
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Description
Diuretic hormone class 1 (Diuretic hormone class I) (Diuretic peptide)(DP) (DH(46)).
Source Organism
Diploptera punctata (Pacific beetle cockroach).
Taxomomy
Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Orthopteroidea; Dictyoptera; Blattaria; Blaberidae;Diplopterinae; Diploptera.
Subcellular Localization
Secreted protein.
Developmental Stage
Similarity
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Post translational Modification
Function
Regulation of fluid secretion. Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules. Has a greater effect on the transport of Na(+) then K(+) ions. In vitro, has synergistic effects with the smaller diuretic hormone DH(31) which co-occurs with it
