Fluocortolone

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

Show 3-D Structure

A glucocorticoid with anti-inflammatory activity used topically for various skin disorders.

General Properties

*Molecular Weight

376.46

*Molecular Formula

C₂₂H₂₉FO₄

*IUPAC NAME

(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1C(=O)CO)C)O)C)F

*Isomeric Smiles

C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@H]1C(=O)CO)C)O)C)F

PhysioChemical Properties

*Melting Point

188(EXP)

*LogP

2.06(EST)

*Water Solubility

290(EXP) at 37C

External Links

• [1]Pubchem
• [2]KEGG Drug

Categories:Hormones