Finasteride

From DrugPedia: A Wikipedia for Drug discovery

[edit] Description

Show 3-D Structure

An orally active TESTOSTERONE 5-ALPHA-REDUCTASE inhibitor. It is used as a surgical alternative for treatment of benign prostatic hyperplasia.

[edit] General Properties

*Molecular Weight

372.54

*Molecular Formula

C₂₃H₃₆N₂O₂

*IUPAC NAME

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

*Canonical Smiles

CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C

*Isomeric Smiles

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C

[edit] PhysioChemical Properties

*Melting Point

3.03(EXP)

*LogP

11.7(EST) at 25C

*Water Solubility

[edit] External Links

• [1]Pubchem
• [2]KEGG Drug
• [3]Human Metabolome DataBase
• [4]Drugbank